An avian retrovirus uses canonical expression and processing mechanisms 1 to generate viral microRNA
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An Avian Retrovirus Uses Canonical Expression and Processing Mechanisms To Generate Viral MicroRNA
To date, the vast majority of known virus-encoded microRNAs (miRNAs) are derived from polymerase II transcripts encoded by DNA viruses. A recent demonstration that the bovine leukemia virus, a retrovirus, uses RNA polymerase III to directly transcribe the pre-miRNA hairpins to generate viral miRNAs further supports the common notion that the canonical pathway of miRNA biogenesis does not exist ...
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